Wg Signaling via Zw3 and Mad Restricts Self-Renewal of ... - OUP …
This novel function of Zw3 phosphorylated but non-Receptor phosphorylated Mad cannot be achieved when MGM and DN-Zw3 are expressed (failure to restrict self-renewing mitosis in Sens SOP leads to ectopic sensory organs) and is hyperactive when CA-Zw3 and Dsh are expressed (complete restriction of Sens SOP mitosis leading to loss of sensilla).